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Key BenefitsThe Active Pharmaceutical Ingredient List brings together structured data on roughly 47,000 active ingredients and excipients used in medicinal products worldwide. Each substance is described in a monograph covering identification, physico-chemical properties and the links to related derivatives, salts and preparations.
The data is sourced from ABDATA Pharma-Daten-Service, Eschborn, Germany, and is updated on a bi-weekly basis. The list is available with the Drug Dictionaries and Premium subscription packages.
Every monograph carries a preferred designation together with its synonyms and the source of each name, so substances can be matched without confusion.
For chemical compounds the list records the properties needed for quality and identity testing.
Entries for plants, animals and micro-organisms add the characteristics specific to natural materials.
Where they apply, statutory and safety classifications are attached to the substance entry.
The monographs describe substances used in medicine and pharmacy worldwide. A substance entry consists of a main entry to which several follow-up entries can be assigned, and searches can be run on any designation of the main and follow-up monographs, on preferred designations and synonyms alike, as well as on reference numbers and substance classification.
For chemical compounds the WHO international nonproprietary name (INN) is used as the preferred designation. Where no INN exists, the European Pharmacopoeia or German pharmacopoeia name is used. Classifying entries group substances by chemical, pharmacological, cosmetic-technological or pesticide criteria, and add markers such as the PRISCUS list of potentially inappropriate medication for older people, substances of concern in compounding, and occupationally relevant substances.
For source plants the scientific plant name is chosen as the preferred designation, while plant parts and preparations carry standardised German names. Entries for plant, animal or microbial substances also record occurrence, quality requirements from pharmacopoeias, and qualitative and quantitative constituents with their sources.
The list draws on the recognised pharmacopoeias and reference works, including the European Pharmacopoeia (Ph. Eur.), the German Pharmacopoeia (DAB), the British and United States Pharmacopoeias, the WHO INN lists, the Merck Index and Martindale.
